How Living Things Stay “Themselves” (Even When Everything Inside Changes)

You know that weird moment when you’ve had a rough week, skipped sleep, eaten random snacks, and still wake up feeling like… you’re still you? The paper by Varela, Maturana, and Uribe digs into that everyday mystery from a very grounded angle: not “what are living things made of?”, but “what kind of ongoing pattern makes something a living unit at all?” Their starting point is that focusing only on parts can miss what actually matters: the organization that makes the whole hold together as one distinct “someone” or “something,” whether or not it’s reproducing.

Their key idea is called autopoiesis, which basically means “self-making.” A living system, in their description, is a network of processes that continually produces the very components that sustain the network. At the same time, it builds and maintains a boundary that makes it a recognizable unit in its space. They use the cell as the easy example: a vast web of chemical reactions keeps making molecules that keep those reactions possible, and together those molecules keep the cell as a physical, separate “thing,” even though the actual matter inside is constantly being replaced. In that picture, what makes something alive is not a specific ingredient, but a looping, self-maintaining organization. That’s also why they contrast living systems with allopoietic ones: many machines produce something other than themselves, while an autopoietic system’s “output” is basically its own continued existence as that same kind of unity.

This also changes the way we think about reproduction. The authors argue that reproduction and evolution are essential. Still, they aren’t the basic definition of being alive, because you can’t reproduce unless you already have a living unity to reproduce in the first place. In their view, reproduction happens as a special case of this self-maintaining organization: the unit can split so that the same kind of self-producing network continues in two fragments. To make the idea less abstract, they present a minimal computer model in a simple grid-world: elements bump around randomly, a “catalyst” helps create “links,” and links bond into chains. Sometimes a chain closes into a loop that traps the catalyst inside. Once that happens, new links formed inside can replace boundary links that fall apart. Hence, the boundary stays intact even though parts keep turning over—like fixing a fence plank-by-plank without ever letting the yard stop being enclosed. They even give a practical “checklist” style key (six points) for deciding if something counts as autopoietic: can you find a boundary, identify components, see a rule-governed system, confirm the boundary is produced by interactions of elements, and confirm the components (including boundary ones) are continually made and participate in creating others.

The everyday takeaway is surprisingly useful: it’s a reminder to look for the pattern that keeps something going, not just the content itself. Your body, habits, relationships, even a group project, can “feel alive” or “fall apart” depending on whether the ongoing loop that sustains it is still running—and whether there’s a boundary that protects that loop from getting wrecked by every outside bump. In the paper, when the network of production breaks, the unity disintegrates; when it can compensate for disturbances, it stays autonomous. That’s a simple lens you can apply day-to-day: if you want a system (you, a routine, a shared apartment, a club) to stay stable while everything changes, focus on the repeating actions that rebuild the structure and the boundary conditions that make those actions possible. The authors even point toward how this thinking could guide attempts to build “life-like” systems in chemistry, like imagining a bubble-like structure whose membrane components are produced or modified by reactions that happen within the special conditions created by the membrane itself—because what matters most is not the material, but the self-maintaining loop that makes a unit a unit.

Reference:
Varela, F. G., Maturana, H. R., & Uribe, R. (1974). Autopoiesis: The organization of living systems, its characterization and a model. Biosystems5(4), 187–196. https://doi.org/10.1016/0303-2647(74)90031-8

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When Small Changes Create Big Patterns: The Everyday Magic of Synergetics

You know that moment when a group chat is quiet. Then one tiny thing happens—someone posts a plan, a meme, or a rumor—and suddenly everyone is talking, making decisions, and the whole “vibe” shifts? Haken says science often sees this kind of jump too: lots of small parts (atoms, cells, people, machines) can start “working together” in a way that creates a clear, large-scale pattern, and that pattern can change suddenly when you tweak just one outside condition. Synergetics is his term for studying these shared “pattern-jump” moments across multiple fields, rather than keeping each subject in its own separate box.

To illustrate this, Haken points to systems that appear totally unrelated but behave in surprisingly similar ways when they cross a tipping point. A laser, with low power, acts like a regular lamp with messy, short light bursts. Still, past a specific input, it suddenly produces a long, steady beam because the tiny “oscillators” inside fall into step together. A fluid heated from below can transition from calm heat flow to organized motion, characterized by neat rolls or hexagons. Some chemical reactions can flip into rhythmic color changes or ring-like patterns. Even a loaded structure, like a thin shell, can go from smooth to a buckled pattern with repeating cells. The point isn’t the details of each example; it’s that “order” can appear because the parts begin cooperating, and the switch can be dramatic.

So, how do you discuss “order” without tracking every single part? Haken’s answer is the idea of an order parameter: a small set of numbers that captures the big pattern you actually notice (like “how magnetized” something is, or “how strong” a large-scale wave is). In contrast, the countless minor details fade into the background. He explains a simple yet powerful trick: often, the slow, significant changes (the order parameter) end up steering the faster, less important ones, so the small parts quickly “fall in line” with the larger pattern. This also helps explain why different outcomes can compete. Sometimes several possible patterns are “almost ready” at the same time, and the final result depends on how those options cooperate or fight each other, plus the system’s starting point and random little pushes from fluctuations. In everyday terms, it’s like a team project where a few key decisions set the direction, and everyone else adjusts. Yet, a small bit of randomness (who speaks first, a sudden deadline, a surprise idea) can decide which plan wins.

Once a new pattern exists, Haken says it isn’t the end of the story. If you continually change the outside conditions, the latest pattern can also become unstable, leading to a whole chain of changes: more complex patterns, pulses, and sometimes irregular, chaotic behavior that appears in very different systems. And randomness isn’t just “noise” to ignore—it can help a finite system explore different stable options, which matters for things like reliability, adaptability, and switching (basically, whether something can change modes without breaking). The big everyday takeaway from Haken’s synergetics is this: when you’re looking at a complicated situation—your habits, a friend group, a crowded campus, a workplace—don’t assume you must understand every tiny detail to understand the outcome. Often, a few “big knobs” (the effective order parameters) and a few tipping points explain why patterns form, why they suddenly shift, and why a slight push at the right moment can change everything.

Reference:
Haken, H. (1984). Synergetics. Physica B+C127(1–3), 26–36. https://doi.org/10.1016/S0378-4363(84)80007-8

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Why Big Changes Often Happen “All at Once” (and What That Means for You)

You know that feeling when nothing seems to change for ages—same routine, same habits, same you—and then suddenly a lot shifts at once? Perhaps a new friend group forms quickly, you switch majors, you move to a new city, or one tough week forces you to get serious about sleep and financial management. Gould and Eldredge argue that the history of life often follows this pattern: long periods where a species remains essentially unchanged, with only minor fluctuations, followed by brief periods during which a new species emerges and change is concentrated.     

In their “punctuated equilibria” view, the main action isn’t a slow, steady makeover happening little by little inside one significant, stable population. Instead, the most noticeable change is tied to speciation—when one line splits and a new species forms—often in small, isolated groups, and on the fossil record clock, which can appear almost instantaneous.  The practical takeaway is surprisingly personal: if you expect your life to improve in a perfectly smooth line, you’ll feel like you’re failing whenever progress comes in jumps. Tracking your habits or journaling can reveal weeks of stability, which are just as crucial as the leaps, helping you understand what’s steady, fragile, and triggers change.

They also warn that people can get fooled by their own expectations. Paleontologists, they argue, spent a long time hunting only for slow, steady change and treating gaps and standstills as mistakes or “nothing to see,” which made the “always gradual” story feel more common than it really was.    This highlights a bias: if you only look for one type of evidence, you’ll confirm what you already believe. To make more intelligent decisions about fitness, studying, or relationships, try shifting your focus-notice the quiet periods, not just the dramatic moments. Recognizing that significant leaps often follow specific conditions, such as a new environment or constraint, can help you understand your own patterns more effectively.

Finally, Gould and Eldredge say that significant trends can emerge even if individual species don’t slowly transform step by step. A trend can emerge from which species thrive and spread, while others decline. So, the “direction” you see later is more like the result of winners piling up than a single, continuous self-improvement story.  They even point to human evolution as an example where they report no detected gradual change within a given hominid group. At the same time, a long-term pattern, such as the development of larger brains, could result from the success of different, mostly stable groups over time.  If you bring that down to daily life, it suggests a kinder way to read your own “trend.” You don’t have to force yourself to become a brand-new person through nonstop tiny upgrades. Sometimes the real change comes from choosing a new “branch”: a new circle, a new routine, a new project that fits better—and then letting the stable parts of you do their job until the next meaningful jump.

Reference:
Gould, S. J., & Eldredge, N. (1977). Punctuated equilibria: the tempo and mode of evolution reconsidered. Paleobiology3, 115–151. https://www.jstor.org/stable/2400177

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Why One Number Is Not Enough to Describe a Messy World

Imagine a group chat with dozens of friends trying to pick a place to go on Friday night. One person wants to watch a movie, another insists on karaoke, a few only care that it’s affordable, and someone else wants good photos for social media. The more people join, the more tangled the conversation becomes. If you tried to “summarize” the whole chat with just one number that says how close everyone is to agreeing, it would feel a bit ridiculous. The situation is messy, with mini-groups, shifting alliances, and half-made plans. That, in a strange way, is close to what physicists face when they study certain messy materials called spin glasses, and it is precisely the kind of problem Parisi dives into. 

Spin glasses are special kinds of magnets where tiny atomic “arrows” don’t all want to point in the same direction. Some pairs prefer to align, others prefer to oppose each other. Hence, the material ends up frustrated and disordered, more like your chaotic group chat than a neat row of soldiers. Earlier, scientists such as Edwards, Anderson, Sherrington, and Kirkpatrick attempted to describe this complex system with a single “order parameter,” essentially a single number that indicates the degree of order in the system. But when they pushed their formulas, they ran into absurd results, like predicting a negative entropy at very low temperature—roughly like saying a playlist has less than zero possible song orders. It was a sign that the description was too simple. Parisi’s key move is to show that, in a careful mathematical treatment called the replica approach, you don’t just need one parameter to describe a spin glass—you actually need an infinite number of them. Instead of one rating, you get a whole curve. This function indicates the similarity between different possible internal arrangements of the material.

Parisi builds this step by step. He starts with the old “one-number” picture, then lets the system be described by more and more parameters—first 1, then 3, then 5, and so on—constantly checking how the predicted energy and other properties behave near the critical temperature where the spin glass appears. With only a few parameters, the description already improves significantly, aligning well with more detailed calculations and computer simulations, and the previously observed negative entropy almost vanishes. As the number of parameters grows, the description approaches a limit where the internal structure of the spin glass is encoded in that function of one variable, defined between 0 and 1. In everyday terms, it’s like going from rating a movie with a single score out of 10 to having a whole profile: acting, soundtrack, story, cinematography, and then even more fine-grained sub-scores. The material is not captured by one label but by an entire landscape of overlapping “moods.”

The interesting part is what this hints at beyond the realm of physics. The function Parisi introduces contains all the information needed to compute physical quantities, such as how strongly the material responds to a magnetic field or how much energy it stores; however, its deeper meaning is still not fully clear in the paper. That uncertainty is a reminder that, in real life, too, complex systems—from your social circle to your mental health or even an online community—are rarely described well by a single number, such as a score, rank, or average. We often try anyway: GPA, follower count, likes, and a single “happiness” scale. Parisi’s work quietly suggests another attitude: when reality is messy and conflicted, expect it to need many parameters, perhaps even a whole continuous spectrum, to be described fairly. Instead of asking “What’s the one number that sums this up?”, we can ask “What is the shape of the whole picture?” Learning to think that way can make us more careful with statistics, more skeptical of oversimplified rankings, and more understanding of materials in a lab, and of people in our lives who, like spin glasses, don’t fit neatly into a single box.

Reference:
Parisi, G. (1979). Infinite Number of Order Parameters for Spin-Glasses. Physical Review Letters43(23), 1754–1756. https://doi.org/10.1103/PhysRevLett.43.1754

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How Random Molecules Might Have Sparked the First Life

Imagine you’re sitting at your desk with a messy pile of LEGO bricks. You’re not trying to build anything specific. Still, every so often, pieces snap together in a way that unexpectedly resembles something recognizable—a tiny house, a creature, or a spaceship. Now, picture that instead of LEGO bricks, you have thousands of small molecules floating around on a particle or droplet somewhere on early Earth. According to Dyson, a similar process may have happened billions of years ago: random molecules bumping into each other until, by pure chance, some formed structures that helped create more structures like themselves.

The idea Dyson describes is that life didn’t begin with a perfect genetic system, such as DNA, but with small ‘islands’ of molecules—clusters where a fixed number of monomers gathered and occasionally joined into tiny chains. Most of the time, these chains were useless, but every now and then, one of them would help another chain form. Dyson refers to those as ‘active’ monomers. When enough active ones appeared at once, a kind of order emerged: the molecules on the island became good at helping each other grow. To make this easier to imagine, think of a group of students working on a group project. If only one or two people are doing the work, not much happens. Still, if the group randomly ends up with several motivated people at the same time, suddenly the whole project becomes productive. Dyson’s model suggests that a similar team effect could have happened among primitive molecules.

Dyson’s calculations highlight that, even without natural selection, a small island of a few thousand monomers could have shifted from chaos to order through chance. Early life may have begun as a random event that stabilized once sufficient beneficial molecules accumulated. Dyson describes this early ‘ordered state’ as a messy mix of simple catalysts rather than modern cells. Once such an island became ordered, it could grow, absorb more material, and eventually split into two, making natural selection relevant only later. The main point is that significant changes in nature—and in life—often begin with small, unlikely steps that become possible when many small things come together.

Reflecting on your own life, Dyson’s model offers a simple lesson. Order doesn’t always come from careful planning; sometimes it emerges from many small attempts, even failed ones, that eventually align. Just as those early molecules needed luck and numerous small fluctuations to reach a stable, productive state, young people often require time and space to try, adjust their direction, and gradually form habits that support growth. What matters is staying in the game long enough for your ‘active pieces’—your motivation, interests, and skills-to come together. Once they align, progress feels natural instead of forced, much like how Dyson suggests early life first found its order.

Reference:
Dyson, F. J. (1982). A model for the origin of life. Journal of Molecular Evolution18(5), 344–350. https://doi.org/10.1007/BF01733901

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This blog provides simplified educational science content, created with the assistance of both humans and AI. It may omit technical details, is provided “as is,” and does not collect personal data beyond basic anonymous analytics. For full details, please see our Privacy Notice and Disclaimer. Read About This Blog & Attribution Note for AI-Generated Content to know more about this blog project.